Constitutive modeling of soft tissues

verfasst von
Michele Marino
Abstract

The mechanical response of soft tissues is characterized by nonlinear stress-strain relationships associated with the peculiar mechanical properties of constituents which are structured in a hierarchical multiscale arrangement. Relevant anisotropic properties are inherited from structural heterogeneities associated with significant differences in the stiffness of constituents. Moreover, the high water content endows soft tissues by incompressible or quasi-incompressible behavior. Finally, tissue mechanics can be also affected by inelastic mechanisms, such as damage and viscous effects, as well as active responses, growth, and remodeling. The effective description of tissue mechanics, i.e. the constitutive model, is instrumental in the development of reliable computational models for biomechanical analyses. Present work addresses the fundamental theoretical aspects for the development of constitutive models of soft tissues. Both elastic and inelastic responses are faced. Modeling strategies are discussed in terms of physical requirements, thermodynamical consistency, and mathematical prescriptions. A snapshot of the state of the art is presented, with a focus on multiscale approaches. The latter allow indeed to gain a special insight on the structure-mechanics relationship that characterizes soft tissue response in pathophysiological conditions.

Organisationseinheit(en)
Institut für Kontinuumsmechanik
Typ
Beitrag in Buch/Sammelwerk
Band
1-3
Seiten
81-110
Anzahl der Seiten
30
Publikationsdatum
2019
Publikationsstatus
Veröffentlicht
Peer-reviewed
Ja
ASJC Scopus Sachgebiete
Biochemie, Genetik und Molekularbiologie (insg.)
Elektronische Version(en)
https://doi.org/10.1016/B978-0-12-801238-3.99926-4 (Zugang: Geschlossen)
 

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