Investigation of degraded bone substitutes made of magnesium alloy using scanning electron microscope and nanoindentation

verfasst von
Ann Kathrin Gartzke, Stefan Julmi, Christian Klose, Silke Besdo, Anja Christina Waselau, Andrea Meyer-Lindenberg, Hans-Jürgen Maier, Peter Wriggers
Abstract

Degradable bone substitutes made of magnesium alloys are an alternative to biological bone grafts. The main advantage is that they can be manufactured location- and patient-specific. To develop and scale appropriate implants using computational models, knowledge about the mechanical properties and especially the change in the properties during the degradation process is essential. Therefore, degraded open-pored implants were investigated using scanning electron microscope and nanoindentation to find their material composition and mechanical properties. Using both techniques the correlation of the material composition and the average modulus was determined. It could be shown that the average modulus of the degradation layer is distinctly lower than that of the base material. The local average modulus of degrading implant highly depends on the magnesium concentration and the accumulation of elements from the environment. A decrease in magnesium concentration leads to a decrease in the average modulus. Thus, the degrading implant had a lower stiffness than the initial structure.

Organisationseinheit(en)
Institut für Kontinuumsmechanik
Institut für Werkstoffkunde
Externe Organisation(en)
Ludwig-Maximilians-Universität München (LMU)
Typ
Artikel
Journal
Journal of the Mechanical Behavior of Biomedical Materials
Band
109
ISSN
1751-6161
Publikationsdatum
09.2020
Publikationsstatus
Veröffentlicht
Peer-reviewed
Ja
ASJC Scopus Sachgebiete
Biomaterialien, Biomedizintechnik, Werkstoffmechanik
Elektronische Version(en)
https://doi.org/10.1016/j.jmbbm.2020.103825 (Zugang: Geschlossen)
 

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