Magnesium Alloys for Open-Pored Bioresorbable Implants

verfasst von
Hans Jürgen Maier, Stefan Julmi, Sabine Behrens, Christian Klose, Ann Kathrin Gartzke, Peter Wriggers, Anja Christina Waselau, Andrea Meyer-Lindenberg
Abstract

If bone defects occur, the body’s own healing mechanism can close them below a critical size; for larger defects, bone autografts are used. These are typically cut from the same person’s hip in a second surgery. Consequently, the risk of complications, such as inflammations, rises. To avoid the risks resulting from the second surgery, absorbable, open-pored implants can be used. In the present study, the suitability of different magnesium alloys as absorbable porous bone substitute material has been investigated. Using the investment casting process with its design flexibility, the implant’s structure can be adapted to the ideal pore geometry with respect to bone ingrowth behavior. Different magnesium alloys (Mg-La2, LAE442, and ZX61) were studied and rated in terms of their degradation rate, bone ingrowth behavior, biocompatibility, and resorbability of the individual alloying elements.

Organisationseinheit(en)
Institut für Werkstoffkunde
Institut für Kontinuumsmechanik
Externe Organisation(en)
Ludwig-Maximilians-Universität München (LMU)
Typ
Artikel
Journal
JOM
Band
72
Seiten
1859-1869
Anzahl der Seiten
11
ISSN
1047-4838
Publikationsdatum
25.02.2020
Publikationsstatus
Veröffentlicht
Peer-reviewed
Ja
ASJC Scopus Sachgebiete
Werkstoffwissenschaften (insg.), Ingenieurwesen (insg.)
Elektronische Version(en)
https://doi.org/10.1007/s11837-020-04078-8 (Zugang: Offen)
 

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