Numerical simulation and experimental validation of biofilm in a multi-physics framework using an SPH based method

verfasst von
Meisam Soleimani, Peter Wriggers, Henryke Rath, Meike Stiesch
Abstract

In this paper, a 3D computational model has been developed to investigate biofilms in a multi-physics framework using smoothed particle hydrodynamics (SPH) based on a continuum approach. Biofilm formation is a complex process in the sense that several physical phenomena are coupled and consequently different time-scales are involved. On one hand, biofilm growth is driven by biological reaction and nutrient diffusion and on the other hand, it is influenced by fluid flow causing biofilm deformation and interface erosion in the context of fluid and deformable solid interaction. The geometrical and numerical complexity arising from these phenomena poses serious complications and challenges in grid-based techniques such as finite element. Here the solution is based on SPH as one of the powerful meshless methods. SPH based computational modeling is quite new in the biological community and the method is uniquely robust in capturing the interface-related processes of biofilm formation such as erosion. The obtained results show a good agreement with experimental and published data which demonstrates that the model is capable of simulating and predicting overall spatial and temporal evolution of biofilm.

Organisationseinheit(en)
Institut für Kontinuumsmechanik
Externe Organisation(en)
Medizinische Hochschule Hannover (MHH)
Typ
Artikel
Journal
Computational mechanics
Band
58
Seiten
619-633
Anzahl der Seiten
15
ISSN
0178-7675
Publikationsdatum
10.2016
Publikationsstatus
Veröffentlicht
Peer-reviewed
Ja
ASJC Scopus Sachgebiete
Numerische Mechanik, Meerestechnik, Maschinenbau, Theoretische Informatik und Mathematik, Computational Mathematics, Angewandte Mathematik
Elektronische Version(en)
https://doi.org/10.1007/s00466-016-1308-9 (Zugang: Geschlossen)
 

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