Development of Sponge Structure and Casting Conditions for Absorbable Magnesium Bone Implants

authored by: Stefan Julmi, Christian Klose, Ann Kathrin Krüger, Peter Wriggers, Hans Jürgen Maier
Abstract: In the case of bone defects, there are two different methods to close such defects. One option is to use bone autografts, but therefore the bone graft has to be cut off from the same person’s hip. In this case the patient has to undergo an additional surgery, which bears complications, like causing inflammations. Absorbable, open-pored implants minimize these risks. Synthetic bone implants are typically made of ceramics, bioglass or polymers. In this study, magnesium alloys were investigated as absorbable porous bone substitute materials in which the bone can grow into. The main advantages are the design flexibility to produce individual implants by investment casting and mechanical properties similar to the bone. In order to adapt the degradation behavior to the bone’s ingrowth behavior, the implant material has to be alloyed and coated. Moreover, to meet the mechanical requirements, finite element simulations of the sponge structure were used during the design phase of the structures and compression tests were conducted for experimental validation.
Organisation(s): Institute of Materials Science
Institute of Continuum Mechanics
Type: Conference contribution
Pages: 307-317
No. of pages: 11
Publication date: 01.02.2017
Publication status: Published
Peer reviewed: Yes
ASJC Scopus subject areas: Electronic, Optical and Magnetic Materials, Energy Engineering and Power Technology, Mechanics of Materials, Metals and Alloys, Materials Chemistry
Electronic version(s): https://doi.org/10.1007/978-3-319-51493-2_29 (Access: Closed)
: Details in the research portal "Research@Leibniz University"

BibTeX

@inproceedings{4037a54bf3924e6ba6f77a5962150d8e,
title = "Development of Sponge Structure and Casting Conditions for Absorbable Magnesium Bone Implants",
abstract = "In the case of bone defects, there are two different methods to close such defects. One option is to use bone autografts, but therefore the bone graft has to be cut off from the same person{\textquoteright}s hip. In this case the patient has to undergo an additional surgery, which bears complications, like causing inflammations. Absorbable, open-pored implants minimize these risks. Synthetic bone implants are typically made of ceramics, bioglass or polymers. In this study, magnesium alloys were investigated as absorbable porous bone substitute materials in which the bone can grow into. The main advantages are the design flexibility to produce individual implants by investment casting and mechanical properties similar to the bone. In order to adapt the degradation behavior to the bone{\textquoteright}s ingrowth behavior, the implant material has to be alloyed and coated. Moreover, to meet the mechanical requirements, finite element simulations of the sponge structure were used during the design phase of the structures and compression tests were conducted for experimental validation.",
keywords = "Absorbable magnesium, Bone implants, Sponge structure",
author = "Stefan Julmi and Christian Klose and Kr{\"u}ger, {Ann Kathrin} and Peter Wriggers and Maier, {Hans J{\"u}rgen}",
note = "Funding information: This research is sponsored by the German Research Foundation (DFG) within the project “Interfacial effects and ingrowing behavior of magnesium-based foams as bioresorbable bone substitute material” (grant no. MA 1175/52-1).; 146th Annual Meeting and Exhibition Supplemental, TMS 2017 ; Conference date: 26-02-2017 Through 02-03-2017",
year = "2017",
month = feb,
day = "1",
doi = "10.1007/978-3-319-51493-2_29",
language = "English",
isbn = "9783319514925",
series = "Minerals, Metals and Materials Series",
publisher = "Springer International Publishing AG",
pages = "307--317",
booktitle = "TMS 2017 146th Annual Meeting & Exhibition Supplemental Proceedings",
address = "Switzerland",
}